Biotinylated Cynomolgus CD117 / c-kit Protein, His,Avitag (MALS verified), Human
Biozol Catalog Number:
ABS-CD7-C82E4-25UG
Supplier Catalog Number:
CD7-C82E4-25ug
Alternative Catalog Number:
ABS-CD7-C82E4-25UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Conjugation:
Biotin
Mast/stem cell growth factor receptor Kit (cKit), a member of the protein kinase superfamily, Tyr protein kinase family and CSF1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 ckit, tyrosineprotein kinase Kit and CD117,which contains five Iglike C2type (immunoglobulinlike) domains and one protein kinase domain. CD117 acts as cellsurface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, CD117 can activate several signaling pathways. Furthermore, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. - Proteine/Peptide
Immobilized Human SCF, His Tag (Cat. No. SCF-H52H3) at 2 µg/mL (100 µL/well) can bind Biotinylated Cynomolgus CD117 Protein, His,Avitag (Cat. No. CD7-C82E4) with a linear range of 0.02-0.313 µg/mL (QC tested).
Immobilized GMP Human SCF Protein (Cat. No. GMP-SCFH25) at 2 µg/mL (100 µL/well) can bind Biotinylated Cynomolgus CD117 Protein, His,Avitag (Cat. No. CD7-C82E4) with a linear range of 0.078-1.25 µg/mL (Routinely tested).
Biotinylated Cynomolgus CD117 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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