Guinea pig CD117 / c-kit Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-CD7-G52H3-200UG
Supplier Catalog Number:
CD7-G52H3-200ug
Alternative Catalog Number:
ABS-CD7-G52H3-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Guinea pig
Conjugation:
Unconjugated
This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene vkit and is often referred to as protooncogene cKit. The canonical form of this glycosylated transmembrane protein has an Nterminal extracellular region with five immunoglobulinlike domains, a transmembrane region, and an intracellular tyrosine kinase domain at the Cterminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membranebound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2020] - Proteine/Peptide
Guinea pig CD117 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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