Unconjugated Human CD47 Protein, His,Avitag(TM) (HPLC verified)

Product Overview

• Article Name: Unconjugated Human CD47 Protein, His,Avitag(TM) (HPLC verified)
• Biozol Catalog Number: ABS-CD7-HA2E9-50UG
• Supplier Catalog Number: CD7-HA2E9-50ug
• Alternative Catalog Number: ABS-CD7-HA2E9-50UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrinassociated protein (IAP) and Protein MER6. CD47 contains 1 Iglike Vtype (immunoglobulinlike) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cellcell adhesion, enhances superantigendependent Tcellmediated proliferation and costimulates Tcell activation. - Proteine/Peptide

Product Properties

• Molecular Weight: 16.9 kDa
• Tag: C-10*His & C-Avi
• NCBI: 08722
• Buffer: 10 mM Bicine, pH8.3
• Purity: 95%
• Form: Powder
• Target: CD47

Application Notes

• Application Notes: CD7-HA2E9 is the unconjugated version of CD7-H82E9 (Biotinylated Human CD47, His,Avitag). It can be utilized for assay development or customized biotinylation according to the experimental designs.

Images

Immobilized Human SIRP alpha, Fc Tag (Cat. No. SIA-H5251) at 2 µg/mL (100 µL/well) can bind Unconjugated Human CD47, His,Avitag (Cat. No. CD7-HA2E9) with a linear range of 2-13 ng/mL (QC tested).

Immobilized Unconjugated Human CD47, His,Avitag (Cat. No. CD7-HA2E9) at 1 µg/mL (100 µL/well) can bind Monoclonal Anti-Human CD47 Antibody, Human IgG4 with a linear range of 0.06-4 ng/mL (QC tested).

Unconjugated Human CD47, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.