Human CD39 (R138A, M139A, E142K) Protein, His Tag (active enzyme), Unconjugated

Product Overview

• Article Name: Human CD39 (R138A, M139A, E142K) Protein, His Tag (active enzyme), Unconjugated
• Biozol Catalog Number: ABS-CD9-H52H7-1MG
• Supplier Catalog Number: CD9-H52H7-1mg
• Alternative Catalog Number: ABS-CD9-H52H7-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, EctoATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing plateletactivating ADP to AMP. Hydrolyzes ATP and ADP equally well. NTPDase1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells(Tregs) mediate immunosuppression through multiple, nonredundant, cellcontact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39CD73adenosine pathway. CD39 ectonucleotidase is the ratelimiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities. - Proteine/Peptide

Product Properties

• Molecular Weight: 52.2 kDa
• Tag: C-10*His
• NCBI: 49961
• Buffer: 50 mM Tris,150 mM NaCl, PH7.5
• Purity: 95%
• Form: Powder
• Target: CD39

Images

Immobilized Human CD39 / ENTPD1 (R138A, M139A, E142K), His Tag (Cat. No. CD9-H52H7) at 1 µg/mL (100 µL/well) can bind Anti-CD39 Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).

Human CD39 (R138A, M139A, E142K) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.