Biotinylated Human CD39 / ENTPD1 Protein, His,Avitag(TM) (active enzyme)
Biozol Catalog Number:
ABS-CD9-H82E5-25UG
Supplier Catalog Number:
CD9-H82E5-25ug
Alternative Catalog Number:
ABS-CD9-H82E5-25UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, EctoATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing plateletactivating ADP to AMP. Hydrolyzes ATP and ADP equally well. NTPDase1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells(Tregs) mediate immunosuppression through multiple, nonredundant, cellcontact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39CD73adenosine pathway. CD39 ectonucleotidase is the ratelimiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities. - Proteine/Peptide
Biotinylated Human CD39, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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