Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated

Product Overview

• Article Name: Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-CDA-H52W5-1MG
• Supplier Catalog Number: CDA-H52W5-1mg
• Alternative Catalog Number: ABS-CDA-H52W5-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfidelinked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 Tcells. Additionally, CD8B plays a critical role in thymic selection of CD8+ Tcells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched. - Proteine/Peptide

Product Properties

• Molecular Weight: 19.5 kDa & 22.1 kDa
• Tag: C-10*His | Native
• NCBI: 01732
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: CD8 alpha & beta

Images

CDA-H52W5-1mg

Immobilized Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-H52W5) at 2 µg/mL (100 µL/well) can bind Anti-CD8 alpha Antibody, Mouse IgG2a (clone: OKT8) with a linear range of 0.06-4 ng/mL (QC tested).

Immobilized Anti-CD8 alpha Antibody,Mouse IgG2a (clone: OKT8) at 1 µg/mL (100 µL/well) can bind Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-H52W5) with a linear range of 2-39 ng/mL (Routinely tested).

Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.