Human Fc gamma RIIB/C (CD32b/c) Protein, Strep Tag (MALS & SPR verified), Unconjugated

Product Overview

• Article Name: Human Fc gamma RIIB/C (CD32b/c) Protein, Strep Tag (MALS & SPR verified), Unconjugated
• Biozol Catalog Number: ABS-CDB-H5284-500UG
• Supplier Catalog Number: CDB-H5284-500ug
• Alternative Catalog Number: ABS-CDB-H5284-500UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Receptors for the Fc region of IgG (Fc gamma R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc gamma Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. There are three genes for human Fcgamma RII /CD32 (A, B, and C) and one for mouse Fcgamma RII B (CD32B). CD32 is a low affinity receptor for IgG. Low affinity immunoglobulin gamma Fc region receptor IIb (FCGR2B) is also known as CD32b, FCG2, IGFR2. CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Coligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target for monoclonal antibody therapy for malignancies. - Proteine/Peptide

Product Properties

• Molecular Weight: 22.7 kDa
• Tag: C-Twin-Strep
• NCBI: 31994
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: Fc gamma RIIB/C / CD32b/c

Images

Human CD32b/c Protein, Strep Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

CDB-H5284-500ug