Alexa Fluor(TM) 488-Labeled Mouse CD3 epsilon Protein, Fc Tag, AF488, Human

Product Overview

• Article Name: Alexa Fluor(TM) 488-Labeled Mouse CD3 epsilon Protein, Fc Tag, AF488, Human
• Biozol Catalog Number: ABS-CDE-MA256-200UG
• Supplier Catalog Number: CDE-MA256-200ug
• Alternative Catalog Number: ABS-CDE-MA256-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Conjugation: AF488

Product Description

CD3e molecule, epsilon is also known as CD3E, is a Tcell surface singlepass type I membrane glycoprotein. CD3E contains 1 Iglike (immunoglobulinlike) domain and 1 ITAM domain. CD3E, together with CD3gamma, CD3delta and CD3zeta, and the Tcell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptorCD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signaltransduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in Tcell development. CD3E plays an essential role in Tcell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2. - Proteine/Peptide

Product Properties

• Molecular Weight: 36 kDa
• Tag: C-Fc
• NCBI: 22646
• Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: CD3 epsilon

Images

Immobilized Alexa Fluor 488-Labeled Mouse CD3 epsilon Protein, Fc Tag (Cat. No. CDE-MA256) at 5 µg/mL (100 µL/well) can bind CD3e Monoclonal Antibody with a linear range of 1-63 ng/mL (QC tested).

Immobilized Alexa Fluor 488-Labeled Mouse CD3 epsilon Protein, Fc Tag (Cat. No. CDE-MA256) at 5 µg/mL (100 µL/well) can bind CD3e Monoclonal Antibody with a linear range of 1-63 ng/mL (Routinely tested). Labeling with fluorescent dyes did not affect their activity.

Alexa Fluor 488-Labeled Mouse CD3 epsilon Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.