Biotinylated Human LILRB1 / CD85j / ILT2 Protein, Fc,Avitag(TM)

Product Overview

• Article Name: Biotinylated Human LILRB1 / CD85j / ILT2 Protein, Fc,Avitag(TM)
• Biozol Catalog Number: ABS-CDJ-H82F7-25UG
• Supplier Catalog Number: CDJ-H82F7-25ug
• Alternative Catalog Number: ABS-CDJ-H82F7-25UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

CD85 antigenlike family member J (CD85J) is also known as Leukocyte immunoglobulinlike receptor subfamily B member 1 (LILRB1 or LIR1), Immunoglobulinlike transcript 2 (ILT2), Monocyte/macrophage immunoglobulinlike receptor 7 (MIR7), which belongs to leukocyte immunoglobulinlike receptor (LIR) family. CD85J / LILRB1 Contains 4 Iglike C2type (immunoglobulinlike) domains. CD85J / LIR1 is expressed predominantly on Bcells and monocytes. CD85J is receptor for class I MHC antigens and recognizes a broad spectrum of HLAA, HLAB, HLAC and HLAG alleles and is also receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and downregulation of the immune response. CD85J / LILRB1 interaction with HLAB or HLAE leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. CD85J / LILRB1 inhibits FCGR1Amediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. - Proteine/Peptide

Product Properties

• Molecular Weight: 75.6 kDa
• Tag: C-Fc & C-Avi
• NCBI: 9
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: LILRB1

Images

Biotinylated Human LILRB1, Fc,Avitag on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.