Human Complement Factor B Protein, His Tag (MALS & SPR verified), Unconjugated

Catalog Number: ABS-CFB-H52H3-100UG
Article Name: Human Complement Factor B Protein, His Tag (MALS & SPR verified), Unconjugated
Biozol Catalog Number: ABS-CFB-H52H3-100UG
Supplier Catalog Number: CFB-H52H3-100ug
Alternative Catalog Number: ABS-CFB-H52H3-100UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Complement factor B, a component of the alternative pathway (AP) of complement activation. Factor B is one of the upstream, proximal components unique to the AP and is essential for the activation of the pathway. It is an integral component that drives the amplification loop. It is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated Blymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated Blymphocytes. - Proteine/Peptide
Molecular Weight: 84.9 kDa
Tag: C-10*His
NCBI: 00751
Buffer: PBS, pH7.4
Purity: 95%
Form: Powder
Target: Complement Factor B
Human Complement Factor B Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
CFB-H52H3-100ug