Human Claudin-18.1 Full Length Protein (VLP), Unconjugated 500 ug

Product Overview

• Article Name: Human Claudin-18.1 Full Length Protein (VLP), Unconjugated 500 ug
• Biozol Catalog Number: ABS-CL1-H52P3-500UG
• Supplier Catalog Number: CL1-H52P3-500ug
• Alternative Catalog Number: ABS-CL1-H52P3-500UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP1 (protein kinase C/mitogenactivated protein kinase/activator protein1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010] - Proteine/Peptide

Product Properties

• NCBI: 56856
• Buffer: PBS, Arginine, pH7.4
• Form: Liquid
• Target: Claudin-18.1

Images

Immobilized Human Claudin-18.1 Full Length Protein (VLP) (Cat. No. CL1-H52P3) at 2 µg/mL (100 µL/well) can bind Monoclonal Anti-HumanCludin18.1antibody, Mouse IgG with a linear range of 2-78 ng/mL (QC tested).