Biotinylated Human Claudin-18.2 Protein, His,Avitag(TM)&Flag Tag (Nanodisc), Insect

Product Overview

• Article Name: Biotinylated Human Claudin-18.2 Protein, His,Avitag(TM)&Flag Tag (Nanodisc), Insect
• Biozol Catalog Number: ABS-CL2-H85D4-100UG
• Supplier Catalog Number: CL2-H85D4-100ug
• Alternative Catalog Number: ABS-CL2-H85D4-100UG
• Manufacturer: AcroBiosystems
• Host: Insect
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lung. Of the two CLDN18 isoform transcripts produced by alternative splicing, CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. CLDN18.2 is a highly selective gastric lineage antigen expressed exclusively on shortlived differentiated gastric epithelial cells where it has only limited accessibility to antibody drugs.14,15 CLDN18.2 is maintained during the course of malignant transformation and thus frequently displayed on the surface of human gastric cancer cells. - Proteine/Peptide

Product Properties

• Molecular Weight: 26.8 kDa
• Tag: N-10*His & C-Flag & C-Avi
• NCBI: 56856
• Buffer: 20 mM HEPES, 150 mM NaCl, pH7.5
• Form: Liquid
• Target: Claudin-18.2

Images

Immobilized Biotinylated Human Claudin-18.2 Protein, His,Avitag&Flag Tag (Cat. No. CL2-H85D4) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Monoclonal Anti-Chimeric Claudin-18.2 Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).

CL2-H85D4-100ug