Biotinylated Human Claudin-6 / CLDN6 Full Length Protein (VLP)

Product Overview

• Article Name: Biotinylated Human Claudin-6 / CLDN6 Full Length Protein (VLP)
• Biozol Catalog Number: ABS-CL6-H82P3-500UG
• Supplier Catalog Number: CL6-H82P3-500ug
• Alternative Catalog Number: ABS-CL6-H82P3-500UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Tight junctions represent one mode of celltocell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Claudin6, also knows as CLDN6, is a multipass transmembrane protein in the Claudin family. Claudin6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. And it is one of the entry cofactors for hepatitis C virus. The methylation of CLDN6 may be involved in esophageal tumorigenesis. The gene of CLDN6 is adjacent to another family member CLDN9 on chromosome 16. - Proteine/Peptide

Product Properties

• NCBI: 56747
• Buffer: PBS, Arginine, pH7.4
• Form: Liquid
• Target: Claudin-6

Images

Immobilized Biotinylated Human Claudin-6 Full Length Protein (VLP) (Cat. No. CL6-H82P3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-Human Claudin-6 antibody, Human IgG1 with a linear range of 0.05-2 ng/mL (QC tested).

ELISA comparison of biotinylated full-length human Claudin-6 (virus-like particles) using anti-Claudin-6 antibody shows ACRO (Cat. No. CL6-H82P3) has superior bioactivity to Company K (Routinely tested).

CL6-H82P3-500ug