Biotinylated Human Claudin-6 Full Length Protein, His,Avitag(TM)&Flag Tag (Detergent), Insect

Product Overview

• Article Name: Biotinylated Human Claudin-6 Full Length Protein, His,Avitag(TM)&Flag Tag (Detergent), Insect
• Biozol Catalog Number: ABS-CL6-H85D3-100UG
• Supplier Catalog Number: CL6-H85D3-100ug
• Alternative Catalog Number: ABS-CL6-H85D3-100UG
• Manufacturer: AcroBiosystems
• Host: Insect
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Tight junctions represent one mode of celltocell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Claudin6, also knows as CLDN6, is a multipass transmembrane protein in the Claudin family. Claudin6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. And it is one of the entry cofactors for hepatitis C virus. The methylation of CLDN6 may be involved in esophageal tumorigenesis. The gene of CLDN6 is adjacent to another family member CLDN9 on chromosome 16. - Proteine/Peptide

Product Properties

• Molecular Weight: 28.6 kDa
• Tag: N-10*His & C-Flag & C-Avi
• NCBI: 56747
• Buffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Purity: 85%
• Form: Liquid
• Target: Claudin-6

Images

Immobilized Biotinylated Human Claudin-6 Protein, His,Avitag&Flag Tag (Cat. No. CL6-H85D3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-Claudin-6 Antibody, Human IgG1 with a linear range of 0.05-2 ng/mL (QC tested).

Biotinylated Human Claudin-6 Protein, His,Avitag&Flag Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.

CL6-H85D3-100ug