Human CLEC5A / MDL-1 Protein, His Tag, active dimer (MALS & SPR verified), Unconjugated

Product Overview

• Article Name: Human CLEC5A / MDL-1 Protein, His Tag, active dimer (MALS & SPR verified), Unconjugated
• Biozol Catalog Number: ABS-CLA-H5243-100UG
• Supplier Catalog Number: CLA-H5243-100ug
• Alternative Catalog Number: ABS-CLA-H5243-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

CLEC5A, also known as MDL1 and MDL1, is a member of the Ctype lectin/Ctype lectinlike domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is upregulated on monocytes in rheumatoid arthritis. CLEC5A with dnaxactivation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release. - Proteine/Peptide

Product Properties

• Molecular Weight: 39.0 kDa
• Tag: N-10*His
• NCBI: 9
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: CLEC5A

Images

Human CLEC5A, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

CLA-H5243-100ug