Biotinylated Human CLEC12A / MICL / CLL-1 Protein, His,Avitag(TM) (C-terminus) (MALS verified)

Catalog Number: ABS-CLA-H82E9-200UG
Article Name: Biotinylated Human CLEC12A / MICL / CLL-1 Protein, His,Avitag(TM) (C-terminus) (MALS verified)
Biozol Catalog Number: ABS-CLA-H82E9-200UG
Supplier Catalog Number: CLA-H82E9-200ug
Alternative Catalog Number: ABS-CLA-H82E9-200UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Biotin
CLEC12A (Ctype lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML. - Proteine/Peptide
Molecular Weight: 27.3 kDa
Tag: C-10*His & C-Avi
NCBI: 5
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: CLEC12A
Immobilized Biotinylated Human CLEC12A Protein, His,Avitag (Cat. No. CLA-H82E9) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Monoclonal Anti-Human CLEC12A Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
Biotinylated Human CLEC12A Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.