Human CNTF Protein, premium grade, Unconjugated, E. coli

Product Overview

• Article Name: Human CNTF Protein, premium grade, Unconjugated, E. coli
• Biozol Catalog Number: ABS-CNF-H5114-500UG
• Supplier Catalog Number: CNF-H5114-500ug
• Alternative Catalog Number: ABS-CNF-H5114-500UG
• Manufacturer: AcroBiosystems
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Ciliary Neurotrophic Factor (CNTF) is a polypeptide hormone and neurotrophic factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations including astrocytes. It is a hypothalamic neuropeptide that is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also cotranscribed with the upstream ZFP91 gene. Cotranscription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor. - Proteine/Peptide

Product Properties

• Molecular Weight: 22.9 kDa
• Tag: Native
• NCBI: 26441
• Buffer: 50 mM Tris, 150 mM NaCl, pH8.0
• Purity: 90%
• Form: Powder
• Target: CNTF

Images

Human CNTF Protein, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.