Human COL1A1 Protein, His Tag, low endotoxin (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-CO1-H5243-1MG
Supplier Catalog Number:
CO1-H5243-1mg
Alternative Catalog Number:
ABS-CO1-H5243-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Type I collagen is the most abundant structural protein of connective tissues such as skin, bone and tendon. It is synthesized as a procollagen molecule which is characterized by a 300 nm triple helical domain flanked by globular N and Cterminal propeptides. The triple helical domain contains GlyXaaYaa triplets where Xaa and Yaa are frequently proline and hydroxyproline, respectively. The nonhelical propeptides are removed by procollagen N and Cproteinase activities so that the mature triple helices can selfassemble into collagen fibrils that provide tensile strength to tissues. Type I collagen is a heterotrimer that consists of two alpha 1(I) chains and one alpha 2(I) chain, although homotrimers consisting of three identical alpha 1(I) chains have also been described . - Proteine/Peptide