Biotinylated Human Complement C3 Protein, His,Avitag(TM) (MALS verified)

Catalog Number: ABS-CO3-H82E8-200UG
Article Name: Biotinylated Human Complement C3 Protein, His,Avitag(TM) (MALS verified)
Biozol Catalog Number: ABS-CO3-H82E8-200UG
Supplier Catalog Number: CO3-H82E8-200ug
Alternative Catalog Number: ABS-CO3-H82E8-200UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Biotin
C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. - Proteine/Peptide
Molecular Weight: 188.5 kDa
Tag: C-10*His & C-Avi
NCBI: 01024
Buffer: PBS, pH7.4
Purity: 95%
Form: Powder
Target: Complement C3
Immobilized Biotinylated Human Complement C3, His,Avitag (Cat. No. CO3-H82E8) at 1 µg/mL (100 µL/well)on streptavidin precoated (0.5 µg/well) plate can bind Human Anti-C3,Human IgG1 Human Kappa with a linear range of 0.1-4 ng/mL (QC tested).
Biotinylated Human Complement C3, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.