Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN16) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGFbinding protein domain, a vWFC domain, a TSP1 domain, and a cysteine knot heparinbinding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin and divalent cationdependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factorinduced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases. - Proteine/Peptide
Immobilized Human CTGF, His Tag (Cat. No. CTF-H52H5) at 2 µg/mL (100 µL/well) can bind Monoclonal Anti-Human CTGF Antibody, Human IgG1 with a linear range of 0.3-10 ng/mL (QC tested).
Human CTGF, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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