Biotinylated Human DDR1 Protein, His,Avitag(TM) (MALS verified)

Product Overview

• Article Name: Biotinylated Human DDR1 Protein, His,Avitag(TM) (MALS verified)
• Biozol Catalog Number: ABS-DD1-H82E9-25UG
• Supplier Catalog Number: DD1-H82E9-25ug
• Alternative Catalog Number: ABS-DD1-H82E9-25UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Discoidin domain receptor 1 (DDR1) is a member of DDRs, which are members of the receptor tyrosine kinase (RTK). Upon collagen binding, DDR1 undergoes tyrosine autophosphorylation, which consequently triggers downstream genetic and cellular pathways and plays critical roles in the regulation of cellular morphogenesis, differentiation, proliferation, adhesion, migration, and invasion. Research shows that DDR1 is closely related to various human diseases including cancer, fibrosis, atherosclerosis, and other inflammatory disorders. New generation DDR1 inhibitors targeting the allosteric sites outside of the canonical ATPbinding pocket or extracellular domain (allosteric inhibitors) may offer a new opportunity for selective DDR1 inhibition therapy development. - Proteine/Peptide

Product Properties

• Molecular Weight: 47.5 kDa
• Tag: C-10*His & C-Avi
• NCBI: 08345
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: DDR1

Images

DD1-H82E9-25ug

Biotinylated Human DDR1, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.