Human DRD2 Protein, Flag,His Tag (Detergent), Unconjugated 500 ug
Biozol Catalog Number:
ABS-DR2-H52D3-500UG
Supplier Catalog Number:
DR2-H52D3-500ug
Alternative Catalog Number:
ABS-DR2-H52D3-500UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Dopamine receptor D2 (DRD2) is G proteincoupled receptor (GPCR) that belong to the D2like dopamine receptor family, couple to Gi to reduce adenylyl cyclase. DRD2s are expressed in different neuronal cell types within the striatum, dopamine binding leads to the inhibition of dopaminergic synaptic transmission. Altered expression level and function of DRD2s are observed in Parkinsons disease, making DRD2 one of the most common therapeutic targets for Parkinsons disease. DRD2 agonists can reduce the side effects of LDOPA and enhance the therapeutic effect. - Proteine/Peptide