Human DR3 Protein, Fc Tag (MALS verified), Unconjugated

Catalog Number: ABS-DR3-H5253-1MG
Article Name: Human DR3 Protein, Fc Tag (MALS verified), Unconjugated
Biozol Catalog Number: ABS-DR3-H5253-1MG
Supplier Catalog Number: DR3-H5253-1mg
Alternative Catalog Number: ABS-DR3-H5253-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo3, Death receptor 3 (DDR3 or DR3), Apoptosisinducing receptor AIR, Apoptosismediating receptor TRAMP, Lymphocyteassociated receptor of death, Apo3, which is a member of the TNFreceptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NFkappaB signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK. - Proteine/Peptide
Molecular Weight: 45.5 kDa
Tag: C-Fc
NCBI: 93038
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Purity: 90%
Form: Powder
Target: DR3
Immobilized Human TL1A, His Tag (Cat. No. TLA-H5243) at 10 µg/mL (100 µL/well) can bind Human DR3 Protein, Fc Tag (Cat. No. DR3-H5253) with a linear range of 1-78 ng/mL (QC tested).
Immobilized Human DR3, Fc Tag (Cat. No. DR3-H5253) at 5 µg/mL (100 µL/well) can bind pre-mixed increasing concentrations of Anti-TL1A Neutralizing Antibody, Human lgG1 and 1 µg/mL (50µL/well) Biotinylated Human TL1A, His Avitag (Cat.No.TLA-H52Q1) with a half maximal inhibitory concentration (lC50) of 1.95 µg/mL (Routinely tested).
Human DR3 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
DR3-H5253-1mg