Human E-Cadherin / Cadherin-1 Protein, Fc Tag, premium grade, Unconjugated

Product Overview

• Article Name: Human E-Cadherin / Cadherin-1 Protein, Fc Tag, premium grade, Unconjugated
• Biozol Catalog Number: ABS-ECD-H5250-1MG
• Supplier Catalog Number: ECD-H5250-1mg
• Alternative Catalog Number: ABS-ECD-H5250-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Cadherins are calciumdependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin1 (CDH1) is also known as epithelial cadherin (Ecadherin), CD_antigen (CD324), Uvomorulin (UVO) ECAD and CDHE, CDH1 / CD324 contains 5 cadherin domains. CDH1 / CD324 / ECAD is expressed in nonneural epithelial tissues. CDH1 / ECAD is involved in mechanisms regulating cellcell adhesions, mobility and proliferation of epithelial cells and has a potent invasive suppressor role. It is a ligand for integrin alphaE/beta7. ECad promotes nonamyloidogenic degradation of Abeta precursors and has a strong inhibitory effect on APP C99 and C83 production. Defects in CDH1 / CD324 / ECAD are the cause of hereditary diffuse gastric cancer (HDGC). - Proteine/Peptide

Product Properties

• Molecular Weight: 92.3 kDa
• Tag: C-Fc
• NCBI: 41839
• Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: E-Cadherin

Images

Human E-Cadherin, Fc Tag, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

ECD-H5250-1mg