Human EDNRB Protein, Flag,His Tag (Detergent), Unconjugated

Product Overview

• Article Name: Human EDNRB Protein, Flag,His Tag (Detergent), Unconjugated
• Biozol Catalog Number: ABS-EDB-H52D3-100UG
• Supplier Catalog Number: EDB-H52D3-100ug
• Alternative Catalog Number: ABS-EDB-H52D3-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Endothelin Receptor B (EDNRB) is a type of G proteincoupled Receptor with the Nterminus located outside the cell. Its widespread in the human body. EDNRB binds to ET and transmits information into the cell through the intracellular Ca2+ phospholipiddependent protein kinase second messenger system, which promotes the rapid release of calcium in the endoplasmic reticulum and sarcoplasmic reticulum, resulting in the rapid increase of intracellular calcium concentration. Endothelin exerts its biological effects through its receptor (ETR). Endothelin and ETR constitute the endothelin axis. Endothelin axis has protumor effects in various tumors including malignant melanoma (MM), including promoting tumor growth, antiapoptosis, promoting angiogenesis and promoting tumor metastasis. - Proteine/Peptide

Product Properties

• Molecular Weight: 61.3 kDa
• Tag: N-Flag & C-10*His
• NCBI: 24530
• Buffer: 50 mM HEPES, 150 mM NaCl, DDM, pH7.5, CHS
• Purity: 90%
• Form: Liquid
• Target: EDNRB

Images

Immobilized Human EDNRB Protein, Flag,His Tag (Cat. No. EDB-H52D3) at 1 µg/mL (100 µL/well) can bind Monoclonal Anti-EDNRB Antibody, Human IgG1 with a linear range of 0.039-1.25 ng/mL (QC tested).

Human EDNRB Protein, Flag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

EDB-H52D3-100ug