Human ENO1 Protein, His Tag (HPLC verified), Unconjugated, E. coli

Product Overview

• Article Name: Human ENO1 Protein, His Tag (HPLC verified), Unconjugated, E. coli
• Biozol Catalog Number: ABS-EN1-H5143-100UG
• Supplier Catalog Number: EN1-H5143-100ug
• Alternative Catalog Number: ABS-EN1-H5143-100UG
• Manufacturer: AcroBiosystems
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Enolase 1 (ENO1), also known as alpha-enolase, is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. It is ubiquitously expressed and accounts for the majority of cytosolic enolase activity. Beyond its metabolic role, ENO1 is a multifunctional ''moonlighting protein: on the cell surface it acts as a plasminogen receptor promoting extracellular matrix degradation and tumor invasion, while a nuclear isoform (MBP-1) binds the c-MYC promoter and regulates transcription. Overexpression of ENO1 has been linked to cancer progression, autoimmune diseases, and neurodegeneration, making it both a biomarker and a potential therapeutic target. - Proteine/Peptide

Product Properties

• Molecular Weight: 49.1 kDa
• Tag: N-10*His
• NCBI: 06733
• Buffer: 20 mM Tris, 150 mM NaCl, pH8.0
• Purity: 95%
• Form: Liquid
• Target: ENO1

Images

Human ENO1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.