Human Endoglin / CD105 Protein, His Tag, Unconjugated

Product Overview

• Article Name: Human Endoglin / CD105 Protein, His Tag, Unconjugated
• Biozol Catalog Number: ABS-ENN-H52H9-500UG
• Supplier Catalog Number: ENN-H52H9-500ug
• Alternative Catalog Number: ABS-ENN-H52H9-500UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Endoglin (ENG), endothelial glycoprotein, also known as CD105, is a coreceptor of the transforming growth factorbeta (TGFbeta) family signaling complex, which is highly expressed on endothelial cells and plays a key role in angiogenesis. It regulates the responses associated with binding to transforming growth factor beta1 egg (ActivinA), bone morphogenetic protein 2 (BMP2), and bone morphogenetic protein 7 (BMP7). Endoglin may be involved in autosomal dominant disease, such as hereditary hemorrhagic telangiectasia 1 (HHT1). Circulating soluble ENG is also elevated in pulmonary arterial hypertension(PAH) and is proposed to be a biomarker for the prognosis of group I PAH patients. - Proteine/Peptide

Product Properties

• Molecular Weight: 62.6 kDa
• Tag: C-10*His
• NCBI: 17813
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: Endoglin

Images

Human Endoglin Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.