Biotinylated Human EphA2 Protein, His,Avitag(TM) (MALS verified)

Catalog Number: ABS-EP2-H82E4-200UG
Article Name: Biotinylated Human EphA2 Protein, His,Avitag(TM) (MALS verified)
Biozol Catalog Number: ABS-EP2-H82E4-200UG
Supplier Catalog Number: EP2-H82E4-200ug
Alternative Catalog Number: ABS-EP2-H82E4-200UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Biotin
EphA2 is a member of the Eph receptor tyrosine kinase family, widely involved in cell adhesion, migration, and tissue boundary formation. It is frequently overexpressed in multiple solid tumors, including breast, lung, ovarian, and pancreatic cancers, where it drives tumor progression, angiogenesis, and metastasis. EphA2 signaling is activated by ephrin-A ligands and contributes to oncogenic pathways such as MAPK and PI3K. Because of its high tumor selectivity and surface accessibility, EphA2 is a prominent therapeutic target for antibodies, ADCs, and CAR-T therapies. - Proteine/Peptide
Molecular Weight: 59.8 kDa
Tag: C-10*His & C-Avi
NCBI: 29317
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: EphA2
Immobilized Biotinylated Human EphA2 Protein, His,Avitag (Cat. No. EP2-H82E4) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human Ephrin-A1, Fc Tag (Cat. No. EF1-H5251) with a linear range of 0.1-1 ng/mL (QC tested).
Biotinylated Human EphA2 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.