Human EpCAM / TROP1 Protein, Mouse IgG2a Fc Tag, Unconjugated

Product Overview

• Article Name: Human EpCAM / TROP1 Protein, Mouse IgG2a Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-EPM-H5255-1MG
• Supplier Catalog Number: EPM-H5255-1mg
• Alternative Catalog Number: ABS-EPM-H5255-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

EpCAM is also known as CO171A, EGP, EGP40,GA7332, KSA, M4S, MIC18, MK1, TROP1, hEGP2, and is a panepithelial differentiation antigen that is expressed on almost all carcinomas as 171A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the CadherinCatenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (EpCAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy. EpCAM cross signaling with Ncadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (EpCAM) recently received increased attention as a prognostic factor in breast cancer. - Proteine/Peptide

Product Properties

• Molecular Weight: 54.3 kDa
• Tag: C-mFc(mIgG2a)
• NCBI: 14785
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: EpCAM

Images

Immobilized Human EpCAM, Mouse IgG2a Fc Tag (Cat. No. EPM-H5255) at 1 µg/mL (100 µL/well) can bind Anti-EpCAM Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).

Human EpCAM, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.