Biotinylated Human EpCAM / TROP1 Protein, Avitag(TM),His Tag (MALS verified)

Product Overview

• Article Name: Biotinylated Human EpCAM / TROP1 Protein, Avitag(TM),His Tag (MALS verified)
• Biozol Catalog Number: ABS-EPM-H82E8-200UG
• Supplier Catalog Number: EPM-H82E8-200ug
• Alternative Catalog Number: ABS-EPM-H82E8-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

EpCAM is also known as CO171A, EGP, EGP40,GA7332, KSA, M4S, MIC18, MK1, TROP1, hEGP2, and is a panepithelial differentiation antigen that is expressed on almost all carcinomas as 171A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the CadherinCatenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (EpCAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy. EpCAM cross signaling with Ncadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (EpCAM) recently received increased attention as a prognostic factor in breast cancer. - Proteine/Peptide

Product Properties

• Molecular Weight: 30.0 kDa
• Tag: C-Avi & C-6*His
• NCBI: 14785
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: EpCAM

Images

Immobilized Biotinylated Human EpCAM, Avitag,His Tag (Cat. No. EPM-H82E8) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-EpCAM Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).

Biotinylated Human EpCAM, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.