Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1F5), Unconjugated, Human
Biozol Catalog Number:
ABS-ERN-MY2062B-1MG
Supplier Catalog Number:
ERN-MY2062b-1mg
Alternative Catalog Number:
ABS-ERN-MY2062B-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Antikörper
Species Reactivity:
Rabbit
Conjugation:
Unconjugated
Eribulin is a synthetic analogue of the macrocyclic polyether halichondrin B, which was originally isolated from the Asian sea sponge Halichondria okadai. Eribulin binds specifically to the betatubulin subunit on the (+) end of the microtubule and potently inhibits elongation of the formed microtubule, while having little or no effect on microtubule depolymerization. Eribulins potent antimitotic activity and nonmitotic effects on tumor biology make it an interesting candidate for investigation as a MTA payload for ADCs. - Antikörper
Tag:
Rabbit IgG | Rabbit Kappa
Buffer:
PBS, pH7.4
Form:
Powder
Target:
Eribulin
Immobilized Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1F5) (Cat. No. ERN-MY2062b) at 1 µg/mL, add FarletuzumabEcteribulin in the 100% Human Serum and then add Biotinylated Human FOLR1, Fc,Avitag (Cat. No. FO1-H82F9) at 0.5 µg/mL. Detection was performed using HRP-conjugated Streptavidin (Acro, Cat. No. STN-NH913) (QC tested).
Immobilized Farletuzumab Ecteribulin at 1 µg/mL (100 µL/well) can bind Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1F5) (Cat. No. ERN-MY2062b) with a linear range of 0.06-2 ng/mL (Routinely tested).
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