Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified), Unconjugated, Human

Product Overview

• Article Name: Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified), Unconjugated, Human
• Biozol Catalog Number: ABS-FC4-M52H3-1MG
• Supplier Catalog Number: FC4-M52H3-1mg
• Alternative Catalog Number: ABS-FC4-M52H3-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Conjugation: Unconjugated

Product Description

FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD162, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophagemediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions - Proteine/Peptide

Product Properties

• Molecular Weight: 22.8 kDa
• Tag: C-10*His
• NCBI: 0
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Fc gamma RIV / CD16-2

Images

Mouse CD16-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

FC4-M52H3-1mg