Human Fc epsilon RI alpha Protein, His Tag (MALS verified), Unconjugated

Catalog Number: ABS-FCA-H5228-1MG
Article Name: Human Fc epsilon RI alpha Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number: ABS-FCA-H5228-1MG
Supplier Catalog Number: FCA-H5228-1mg
Alternative Catalog Number: ABS-FCA-H5228-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fcepsilon RIalpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Iglike (immunoglobulinlike) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptorbound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. - Proteine/Peptide
Molecular Weight: 22.9 kDa
Tag: C-10*His
NCBI: 12319
Buffer: PBS, pH7.4
Purity: 95%
Form: Powder
Target: Fc epsilon RI alpha
FCA-H5228-1mg
Immobilized Immunoglobulin E, Human Plasma at 5 µg/mL (100 µL/well) can bind Human Fc epsilon RI alpha, His Tag (Cat. No. FCA-H5228) with a linear range of 0.4-3 ng/mL (QC tested).
Human Fc epsilon RI alpha, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.