Biotinylated Human Fc gamma RI / CD64 Protein, His,Avitag(TM) (SPR & BLI & MALS verified)
Biozol Catalog Number:
ABS-FCA-H82E8-25UG
Supplier Catalog Number:
FCA-H82E8-25ug
Alternative Catalog Number:
ABS-FCA-H82E8-25UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgGtype antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Iglike C2type (immunoglobulinlike) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNgamma and GCSF can induce CD64 expression on these cells. - Proteine/Peptide
Immobilized Ipilimumab at 2 µg/mL (100 µL/well) can bind Biotinylated Human CD64, His,Avitag (Cat. No. FCA-H82E8) with a linear range of 0.1-3 ng/mL (QC tested).
Immobilized Monoclonal Anti-Human CTLA-4 Antibody, Human IgG1 at 1 µg/mL (100 µL/well) can bind Biotinylated Human CD64, His,Avitag (Cat. No. FCA-H82E8) with a linear range of 0.06-1 ng/mL (Routinely tested).
Biotinylated Human CD64, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
FCA-H82E8-25ug
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