Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (SPR & BLI & HPLC-verified), Unconjugated

Catalog Number: ABS-FCM-H5286-50UG
Article Name: Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (SPR & BLI & HPLC-verified), Unconjugated
Biozol Catalog Number: ABS-FCM-H5286-50UG
Supplier Catalog Number: FCM-H5286-50ug
Alternative Catalog Number: ABS-FCM-H5286-50UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta2microglobulin), and forms an MHC class Ilike heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta2microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system. - Proteine/Peptide
Molecular Weight: 31.2 kDa (FCGRT) & 13.1 kDa (B2M)
Tag: C-6*His | C-Strep II
NCBI: 55899
Buffer: PBS, pH7.4
Purity: 95%
Form: Powder
Target: FcRn (FCGRT & B2M)
Immobilized Monoclonal Anti-Human CTLA-4 Antibody, Human IgG1 at 5 µg/mL (100 µL/well) can bind Human FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (Cat. No. FCM-H5286) with a linear range of 1-78 ng/mL (Routinely tested).
Immobilized Human FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (Cat. No. FCM-H5286) at 5 µg/mL (100 µL/well) on a Nickel Coated plate can bind Monoclonal Anti-Human CTLA-4 Antibody, Human IgG1 with a linear range of 0.001-0.063 µg/mL (Routinely tested).
Human FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
FCM-H5286-50ug