FetuinB (FETUB), a second member of the fetuin family in mammals, is also known as Fetuinlike protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuinBtype domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liverderived plasma protein, FETUB is essential for fertilization. - Proteine/Peptide
Human Fetuin B, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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