Human FGF-23 (R179Q) Protein, His Tag, Unconjugated

Product Overview

• Article Name: Human FGF-23 (R179Q) Protein, His Tag, Unconjugated
• Biozol Catalog Number: ABS-FG3-H52H3-1MG
• Supplier Catalog Number: FG3-H52H3-1mg
• Alternative Catalog Number: ABS-FG3-H52H3-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Fibroblast growth factor 23 (FGF23) is is an endocrine member of the family of FGFs and mainly produced in the bone and, upon secretion, forms a complex with a FGF receptor and coreceptor alphaKlotho. FGF23 can exert several endocrine functions, such as acting as a hormone on the kidney, stimulating phosphate excretion and suppressing formation of 1,25(OH)2D3, active vitamin D. Moreover, it has paracrine activities on several cell types, including neutrophils and hepatocytes. FGF23 and phosphate have been revealed to be factors relevant in cancer. FGF23 is particularly significant for those forms of cancer primarily affecting bone (e.g., multiple myeloma) or characterized by bone metastasis. - Proteine/Peptide

Product Properties

• Molecular Weight: 27.3 kDa
• Tag: C-10*His
• NCBI: 9
• Buffer: 20 mM MOPS, 150 mM NaCl, pH7.4
• Purity: 95%
• Form: Powder
• Target: FGF-23

Images

Human FGF-23 (R179Q), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.