Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs-FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF-FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression. - Proteine/Peptide
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Purity:
90%
Form:
Powder
Target:
FGF19
FG9-H5253-1mg
Immobilized Human Klotho beta Protein, His Tag (Cat. No. KLB-H52H4) at 10 µg/mL (100 µL/well) can bind Human FGF19, Fc Tag (Cat. No. FG9-H5253) with a linear range of 0.005-0.156 µg/mL (QC tested).
Human FGF19, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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