Human FGF R3 (IIIb) / FGF R3B / CD333 Protein, Fc Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human FGF R3 (IIIb) / FGF R3B / CD333 Protein, Fc Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-FGB-H5259-1MG
• Supplier Catalog Number: FGB-H5259-1mg
• Alternative Catalog Number: ABS-FGB-H5259-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Fibroblast growth factor receptors (FGFR) are transmembrane kinase proteins with growing importance in cancer biology given the frequency of molecular alterations and vast interface with multiple other signaling pathways. The FGFR3 gene is at the human chromosomal locus 4p16.3 also encodes two isoforms: FGF R3 (IIIb) FGF R3 (IIIc). Upregulated expression of FGFR3 protein is also found in a significant number of tumors. Additionally, FGFR3 has been found to trigger resistance to tamoxifen via the activation of the PLCgamma signaling cascade. - Proteine/Peptide

Product Properties

• Molecular Weight: 65.0 kDa
• Tag: C-Fc
• NCBI: 22607
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: FGF R3 (IIIb)

Images

Immobilized Human FGF basic, premium grade (Cat. No. BFF-H4117) at 5 µg/mL (100 µL/well) can bind Human FGF R3 (IIIb), Fc Tag (Cat. No. FGB-H5259) with a linear range of 2-39 ng/mL (QC tested).

Immobilized Biotinylated Human FGF basic, Avitag,His Tag (Cat. No. FGC-H81E3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human FGF R3 (IIIb), Fc Tag (Cat. No. FGB-H5259) with a linear range of 1-39 ng/mL (Routinely tested).

Human FGF R3 (IIIb), Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

FGB-H5259-1mg