Biotinylated Human Flt-3 / Flk-2 Protein, His,Avitag(TM) (MALS verified)

Product Overview

• Article Name: Biotinylated Human Flt-3 / Flk-2 Protein, His,Avitag(TM) (MALS verified)
• Biozol Catalog Number: ABS-FL3-H82E3-25UG
• Supplier Catalog Number: FL3-H82E3-25ug
• Alternative Catalog Number: ABS-FL3-H82E3-25UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Flt3(Receptortype tyrosineprotein kinase FLT3) is also known as FLK2(Fetal liver kinase2), STK1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosineprotein kinase that acts as cellsurface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways. - Proteine/Peptide

Product Properties

• Molecular Weight: 62.1 kDa
• Tag: C-10*His & C-Avi
• NCBI: 36888
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Flt-3

Images

Immobilized Human Flt-3 Ligand, His Tag (Cat. No. FLL-H5223) at 1 µg/mL (100 µL/well) can bind Biotinylated Human Flt-3, His,Avitag (Cat. No. FL3-H82E3) with a linear range of 0.039-1.25 µg/mL (QC tested).

Biotinylated Human Flt-3, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.