Human Frizzled-7 / FZD7 Protein, Fc Tag, Unconjugated

Catalog Number: ABS-FZ7-H5258-1MG
Article Name: Human Frizzled-7 / FZD7 Protein, Fc Tag, Unconjugated
Biozol Catalog Number: ABS-FZ7-H5258-1MG
Supplier Catalog Number: FZ7-H5258-1mg
Alternative Catalog Number: ABS-FZ7-H5258-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Frizzled7 (FZD7) is also known as FzE3, which belongs to the Gprotein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the betacatenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of betacatenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1. - Proteine/Peptide
Molecular Weight: 43.3 kDa
Tag: C-Fc
NCBI: 15915
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Purity: 95%
Form: Powder
Target: Frizzled-7
Immobilized Human Frizzled-7, Fc Tag (Cat. No. FZ7-H5258) at 1 µg/mL (100 µL/well) can bind Wnt surrogate Human IgG1(D239E,L241M)
Human Frizzled-7, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.