Human GCGR Protein, Flag,His Tag (Detergent), Unconjugated

Product Overview

• Article Name: Human GCGR Protein, Flag,His Tag (Detergent), Unconjugated
• Biozol Catalog Number: ABS-GCR-H52D3-20UG
• Supplier Catalog Number: GCR-H52D3-20ug
• Alternative Catalog Number: ABS-GCR-H52D3-20UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy. - Proteine/Peptide

Product Properties

• Molecular Weight: 83.2 kDa
• Tag: N-Flag & C-10*His
• NCBI: 47871
• Buffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Form: Liquid
• Target: GCGR

Images

Immobilized Human GCGR Protein, Flag,His Tag (Cat. No. GCR-H52D3) at 5 µg/mL (100 µL/well) on a Nickel Coated plate can bind Monoclonal Anti-Human GCGR antibody, Human IgG2 (Volagidemab) (Cat. No. GCR-H52D3) with a linear range of 0.1-3 ng/mL (QC tested).

Immobilized Human GCGR Protein, Flag,His Tag (Cat. No. GCR-H52D3) at 5 µg/mL (100 µL/well) on a Nickel Coated plate can bind Monoclonal Anti-Human GCGR antibody, Human IgG4 (Crotedumab) with a linear range of 0.1-3 ng/mL (Routinely tested).