Human GCGR / Glucagon receptor Protein, His Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human GCGR / Glucagon receptor Protein, His Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-GCR-H52H3-50UG
• Supplier Catalog Number: GCR-H52H3-50ug
• Alternative Catalog Number: ABS-GCR-H52H3-50UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Gprotein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotidebinding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositolcalcium second messenger system. - Proteine/Peptide

Product Properties

• Molecular Weight: 14.9 kDa
• Tag: C-10*His
• NCBI: 47871
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: GCGR

Images

Immobilized Human GCGR, His Tag (Cat. No. GCR-H52H3) at 1 µg/mL (100 µL/well) can bind Human Anti-GCGR (Volagidemab), Human IgG2 with a linear range of 0.1-4 ng/mL (QC tested).

Human GCGR, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.