Human GCGR / Glucagon receptor Full Length Protein (VLP), Unconjugated

Catalog Number: ABS-GCR-H52P5-100UG
Article Name: Human GCGR / Glucagon receptor Full Length Protein (VLP), Unconjugated
Biozol Catalog Number: ABS-GCR-H52P5-100UG
Supplier Catalog Number: GCR-H52P5-100ug
Alternative Catalog Number: ABS-GCR-H52P5-100UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy. - Proteine/Peptide
NCBI: 47871
Buffer: PBS, Arginine, pH7.4
Form: Liquid
Target: GCGR
Immobilized Human GCGR Full Length Protein (VLP) (Cat. No. GCR-H52P5) at 5 µg/mL (100 µL/well) can bind Monoclonal Anti-HumanGCGRantibody,Human IgG4 (Crotedumab) with a linear range of 0.1-20 ng/mL (QC tested).
Immobilized Human GCGR Full Length Protein (VLP) (Cat. No. GCR-H52P5) at 5 µg/mL (100 µL/well) can bind Monoclonal Anti-HumanGCGRantibody,Human IgG2 (Volagidemab) with a linear range of 0.1-20 ng/mL (Routinely tested).