Rat GFR alpha-like Protein, His Tag, Unconjugated, Human

Product Overview

• Article Name: Rat GFR alpha-like Protein, His Tag, Unconjugated, Human
• Biozol Catalog Number: ABS-GFA-R52H5-1MG
• Supplier Catalog Number: GFA-R52H5-1mg
• Alternative Catalog Number: ABS-GFA-R52H5-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Rat
• Conjugation: Unconjugated

Product Description

GFR alphalike is also known as GDNF family receptor alphalike, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor alphalike (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstemrestricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxininduced stresses . Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK and AKT signaling pathways. - Proteine/Peptide

Product Properties

• Molecular Weight: 39.0 kDa
• Tag: C-10*His
• NCBI: 3
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: GFR alpha-like

Images

Immobilized Rat GFR alpha-like, His Tag (Cat. No. GFA-R52H5) at 5 µg/mL (100 µL/well) can bind Human GDF-15, Fc Tag (Cat. No. GD5-H5269) with a linear range of 0.1-8 ng/mL (QC tested).

Rat GFR alpha-like, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.