HHV-5 (strain AD169) Glycoprotein H&L, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-GHL-H5243-500UG
Supplier Catalog Number:
GHL-H5243-500ug
Alternative Catalog Number:
ABS-GHL-H5243-500UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Virus
Conjugation:
Unconjugated
Human cytomegalovirus (HCMV), a prototypical betaherpes virus, is a major cause of morbidity and mortality in immunocompromised transplant recipients and congenitally infected fetuses.Different HCMV glycoprotein complexes are capable of meditating entry through interaction with cellspecific receptors on a panel of host cells. The pentamer (gH/gL/UL128/UL130/UL131A) mediates HCMV entry into epithelial, endothelial, and myeloid cells by its binding to neuropilin 2 (Nrp2). The trimer (gH/gL/gO) can mediate infection of all cell types by binding to plateletderived growth factoralpha (PDGFRalpha). Both pentamer and trimer need to interact with the glycoprotein B (gB), the fusogenic protein, to trigger the virus and host cell membrane fusion. - Proteine/Peptide
Glycoprotein H & Glycoprotein L/gH & gL (HCMV)
Immobilized HHV-5 (strain AD169) Glycoprotein H&L, His Tag (Cat. No. GHL-H5243) at 1 µg/mL (100 µL/well) can bind Anti-HCMV gH [HCMV16], Human, IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
Immobilized Anti-HCMV gH [HCMV16], Human, IgG1 at 1 µg/mL (100 µL/well) can bind HHV-5 (strain AD169) Glycoprotein H&L, His Tag (Cat. No. GHL-H5243) with a linear range of 0.004-0.25 µg/mL (Routinely tested).
HHV-5 (strain AD169) Glycoprotein H&L, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
GHL-H5243-500ug
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