Rhesus macaque Growth Hormone R (GHR) Protein, Fc Tag, Unconjugated, Human

Product Overview

• Article Name: Rhesus macaque Growth Hormone R (GHR) Protein, Fc Tag, Unconjugated, Human
• Biozol Catalog Number: ABS-GHR-C5253-1MG
• Supplier Catalog Number: GHR-C5253-1mg
• Alternative Catalog Number: ABS-GHR-C5253-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Conjugation: Unconjugated

Product Description

Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormonebinding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin typeIII domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol esterpromoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. - Proteine/Peptide

Product Properties

• Molecular Weight: 54.7 kDa
• Tag: C-Fc
• NCBI: 79194
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: Growth Hormone R

Images

Immobilized Human GH, Tag Free at 2 µg/mL (100 µL/well) can bind Rhesus macaque GHR, Fc Tag (Cat. No. GHR-C5253) with a linear range of 0.039-0.625 µg/mL (QC tested).

Rhesus macaque GHR, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.