Human GITR Ligand / TNFSF18 Protein, His Tag, Unconjugated

Product Overview

• Article Name: Human GITR Ligand / TNFSF18 Protein, His Tag, Unconjugated
• Biozol Catalog Number: ABS-GIL-H5249-1MG
• Supplier Catalog Number: GIL-H5249-1mg
• Alternative Catalog Number: ABS-GIL-H5249-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid induced TNFrelated ligand (GITRL or GITR Ligand), Activation inducible TNF related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is upregulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for Tcell activation and Tcell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated Tlymphocytes and endothelial cells. TNFSF18 also mediates activation of NFkappaB. - Proteine/Peptide

Product Properties

• Molecular Weight: 20.5 kDa
• Tag: N-10*His
• NCBI: 69319
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: GITR Ligand

Images

Immobilized Human GITR Ligand, His Tag (Cat. No. GIL-H5249) at 2 µg/mL (100 µL/well) can bind Human GITR, Fc Tag (Cat. No. GIR-H5254) with a linear range of 0.1-4 ng/mL (QC tested).

Immobilized Human GITR Ligand, His Tag (Cat. No. GIL-H5249) at 2 µg/mL (100 µL/well) can bind Human GITR, Mouse IgG2a Fc Tag, low endotoxin with a linear range of 0.2-8 ng/mL (Routinely tested).

Human GITR Ligand, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.