Mouse GITR Ligand / TNFSF18 Protein, Fc Tag, Unconjugated, Human

Catalog Number: ABS-GIL-M526X-100UG
Article Name: Mouse GITR Ligand / TNFSF18 Protein, Fc Tag, Unconjugated, Human
Biozol Catalog Number: ABS-GIL-M526X-100UG
Supplier Catalog Number: GIL-M526x-100ug
Alternative Catalog Number: ABS-GIL-M526X-100UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Mouse
Conjugation: Unconjugated
Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid induced TNFrelated ligand (GITRL or GITR Ligand), Activation inducible TNF related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is upregulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for Tcell activation and Tcell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated Tlymphocytes and endothelial cells. TNFSF18 also mediates activation of NFkappaB. - Proteine/Peptide
Molecular Weight: 41.4 kDa
Tag: N-Fc
NCBI: 89011
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Purity: 95%
Form: Powder
Target: GITR Ligand
Immobilized Mouse GITR Protein, His Tag (Cat. No. GIR-M52H3) at 5 µg/mL (100 µL/well) can bind Mouse GITR Ligand, Fc Tag (Cat. No. GIL-M526x) with a linear range of 2-39 ng/mL (QC tested).
Mouse GITR Ligand, Fc Tag on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.