Human cytomegalovirus (strain AD169) (HHV-5) Glycoprotein H&L&O, His Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human cytomegalovirus (strain AD169) (HHV-5) Glycoprotein H&L&O, His Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-GLO-V5243-500UG
• Supplier Catalog Number: GLO-V5243-500ug
• Alternative Catalog Number: ABS-GLO-V5243-500UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Virus
• Conjugation: Unconjugated

Product Description

Human cytomegalovirus (HCMV), a prototypical betaherpes virus, is a major cause of morbidity and mortality in immunocompromised transplant recipients and congenitally infected fetuses.Different HCMV glycoprotein complexes are capable of meditating entry through interaction with cellspecific receptors on a panel of host cells. The pentamer (gH/gL/UL128/UL130/UL131A) mediates HCMV entry into epithelial, endothelial, and myeloid cells by its binding to neuropilin 2 (Nrp2). The trimer (gH/gL/gO) can mediate infection of all cell types by binding to plateletderived growth factoralpha (PDGFRalpha). Both pentamer and trimer need to interact with the glycoprotein B (gB), the fusogenic protein, to trigger the virus and host cell membrane fusion. - Proteine/Peptide

Product Properties

• Molecular Weight: 162.2 kDa
• Tag: N-10*His
• NCBI: 12824
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Glycoprotein H & Glycoprotein L & Glycoprotein O/gH & gL & gO (HCMV)

Images

Immobilized Human cytomegalovirus (strain AD169) (HHV-5) Glycoprotein H&L&O, His Tag (Cat. No. GLO-V5243) at 1 µg/mL (100 µL/well) can bind Anti-HCMV gH [HCMV16], Human, IgG1 with a linear range of 0.05-2 ng/mL (QC tested).

Human cytomegalovirus (strain AD169) (HHV-5) Glycoprotein H&L&O, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

GLO-V5243-500ug